About atrial fibrillation and cardiac surgery

BOS1728515 for the treatment of atrial fibrillation

Postoperative atrial fibrillation is the most common complication among patients undergoing cardiac surgery. Postoperative atrial fibrillation usually occurs within the first 2-3 days after surgery and is associated with other postoperative complications including ischemic stroke, heart failure, and acute kidney injury. Standard therapy, antiarrhythmic agents and anticoagulants, could cause unwanted effects by inducing proarrhythmia and bleeding.